Mitosis: New Roles for Myosin-X and Actin at the Spindle
نویسندگان
چکیده
Roles for actin and myosin in positioning mitotic spindles in the cell are well established. A recent study of myosin-X function in early Xenopus embryo mitosis now reports that this unconventional myosin is required for pole integrity and normal spindle length by localizing to poles and exerting pulling forces on actin filaments within the spindle.
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Adducin-1 moonlights at the mitotic spindle A n actin-binding protein helps shape the mitotic spindle, Chan et al. report. Researchers long thought that actin and microtubules performed different tasks during mitosis. They believed that micro tubules formed the mitotic spindle that pulls chromosomes apart, whereas actin joined with myosin to produce the contractile furrow that separates the mot...
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عنوان ژورنال:
- Current Biology
دوره 18 شماره
صفحات -
تاریخ انتشار 2008